Operational Unit
Biochemistry & Molecular Biophysics Center
Chemistry & Chemical Engineering
Unit Mandate
Mission & Operational Scope
Investigates the molecular mechanisms of biological processes using biophysical and biochemical approaches, providing structural and mechanistic insights that drive the Foundation's therapeutic development and biosensor programs.
Doctrine
NIH Structural Biology Program Standards · Caltech Chemistry-Biology Interface Guidelines
Core Capabilities
Operational Capabilities
Protein structure determination via X-ray crystallography and cryo-EM
Enzyme kinetics and inhibitor characterization
Lipid membrane biophysics and drug-membrane interaction studies
Single-molecule biophysics using optical tweezers and AFM
Isothermal titration calorimetry for binding thermodynamics
Structural bioinformatics and molecular docking analysis
Division III
Chemistry & Chemical Engineering